Event Calendar

Lectures & Seminars

23.05.2018 18:00 - 19:00 o'clock

MiCoCo together with the CRC FungiNet: Gut networking: How the host, commensal bacteria, and fungi contribute to the pathogenesis of Salmonella gastroenteritis

Lecturer: Ass. Prof. Judith Behnsen, Department of Microbiology and Immunology, University of Illinois at Chicago, College of Medicine

Foodborne gastrointestinal infections are common occurrences that every person usually suffers from at least once in their lives. In a best-case scenario, infection with a pathogen like Salmonella enterica serovar Typhimurium (Salmonella) is severely unpleasant, but it can be life threatening to vulnerable populations. How Salmonella manages to establish colonization in the gut has been studied extensively, but is not completely understood. Recent data support the idea that Salmonella colonization is aided by two unexpected sides: the host and the microbiota. One of the responses that help Salmonella colonize is the upregulation of the host protein interleukin-22 (IL-22). Our studies show that IL-22 has a previously undiscovered role during infection in that it suppresses the intestinal microbiota and enhances colonization of Salmonella. Also certain bacterial members of the microbiota are known to support Salmonella colonization by providing nutrients and electron acceptors. Our current studies focus on the role of the underappreciated fungal component of the gut microbiota and how it might promote Salmonella pathogenesis.  

Date: May 23, 2018

Time: 6 pm

Location: Lecture Hall Erbertstraße (Großer Hörsaal)

All interested are cordially invited!

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