Event Calendar

Lectures & Seminars

16.01.2019 18:00 - 19:00 o'clock

MiCoCo: Honey Bee Gut Microbiota - versatile model for microbial symbiosis

Lecturer: Dr. Philipp Engel, Function and evolution of gut microbiota-host interaction Microbial Symbiosis, Lausanne University, Switzerland

Abstract: Specialized bacterial communities colonize the animal gut and impact health and disease of the host in manifold ways.  However, their complex composition presents a veritable challenge for elucidating fundamental aspects of gut microbiota functions, ecology, and evolution. In my lab, we study the honey bee gut microbiota, a surprisingly simple, yet conserved gut community that is experimentally amenable and shares striking parallels to the mammalian system. Our overall goal is to combine experimental and genomic approaches to systematically understand functioning and evolution of this specialized, host-associated community.

In my talk, I will summarize two recent projects, in which we applied metabolomics and shotgun metagenomics, respectively, to disentangle metabolic capacities of individual community members and identify the community’s population genomic structure. Our results show distinct roles of bee gut symbionts in the conversion of major pollen wall constituents, but also suggest potential cross-feeding activities between them. Moreover, the genome-level information obtained from shotgun metagenomic data revealed the existence of discrete evolutionary lineages within previously defined species (as defined per 16S community profiling). These lineages are characterized by a remarkably high level of divergence and functional gene content variation suggesting diversification by adaptation to different metabolic niches.

Date: Jan 16, 2019

Time: 6 pm

Location: Lecture Hall Erbertstraße (Großer Hörsaal)

All interested are cordially invited!

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