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Lectures & Seminars

22.11.2017 18:00 - 19:00 o'clock

MiCoCo: Investigating fungal chemical ecology by evolutionary analyses of metabolic gene clusters

Lecturer: Prof Dr. Jason C Slot, The Ohio State University, College of Food, Agricultural, and Environmental Sciences Department of Plant Pathology


Diverse small molecules known as secondary metabolites often serve as the ecological interface between filamentous fungi and their associates and competitors. In many fungal lineages, genomes are highly structured into “gene clusters” corresponding to metabolic pathways involved in the synthesis and degradation of secondary metabolites, but the evolutionary mechanisms driving this clustering are not well established. Metabolic gene clusters appear to facilitate fungal adaptation through rapid pathway acquisition by horizontal gene transfer (HGT). Signatures of HGT among fungi can effectively be used to discover novel metabolic pathways involved in both the synthesis and degradation of secondary metabolites, and to thereby identify novel genetic mechanisms underpinning fungal chemical ecology.

Date: November 22nd 2017

Time: 6 pm

Location: Lecture Hall Erbertstraße (Großer Hörsaal)

All interested are cordially invited!

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